Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698735 | 0.88 | MAPT (0.47) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL21816941 | 0.88 | MAPT (0.43) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL23698737 | 0.87 | MAPT (0.42) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL23698642 | 0.86 | MAPT (0.44) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL31229323 | 0.86 | MAPT (0.44) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL23698779 | 0.85 | MAPT (0.49) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL23715733 | 0.85 | MAPT (0.51) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL21816840 | 0.83 | MAPT (0.51) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL21816884 | 0.82 | CTSB (0.47) | MAPTALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL23698661 | 0.81 | MAPT (0.46) | MAPTALDH1A1L3MBTL1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858814-A1 | NITROXOLINE PRODRUG AND USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |