⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14165998 | 1.00 | — | — | |
| SCHEMBL14165999 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28173211 | 0.97 | ATM (0.42) | — | |
| Hydrochloric Acid SCHEMBL28173212 | 0.97 | ATM (0.42) | — | |
| SCHEMBL20241327 | 0.83 | ATM (0.39) | — | |
| SCHEMBL22229916 | 0.83 | ATM (0.39) | — | |
| SCHEMBL28681081 | 0.83 | ATM (0.39) | — | |
| SCHEMBL28592016 | 0.83 | ATM (0.39) | — | |
| SCHEMBL28603834 | 0.83 | ATM (0.39) | — | |
| SCHEMBL28338970 | 0.83 | ATM (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209001-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p. A. (IT) | 2024-06-27 | — | — | US | disclosed |
| CN-113396150-B | Tricyclic JANUS kinase 1 inhibitors and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117015543-A | Novel JAK inhibitor compounds, methods of synthesis and uses thereof | 高德美控股有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023066363-A1 | PARP-1 DEGRADATION AGENT AND USE THEREOF | 海思科医药集团股份有限公司 | 2023-04-27 | — | — | WO | disclosed |
| CN-115297930-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113396150-A | Tricyclic JANUS kinase 1 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2021-09-14 | — | — | CN | disclosed |
| EP-3856742-A1 | TRICYCLIC JANUS KINASE 1 INHIBITORS, AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |