Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699091 | 0.89 | IDO1 (0.41) | IDO1CYP2C9CYP2C8TDO2CYP3A4 | |
| SCHEMBL23707504 | 0.88 | IDO1 (0.51) | IDO1CYP2C9CYP2C8TDO2CYP3A4 | |
| SCHEMBL23699079 | 0.85 | IDO1 (0.37) | IDO1 | |
| SCHEMBL23699114 | 0.78 | IDO1 (0.43) | IDO1 | |
| SCHEMBL23707503 | 0.75 | IDO1 (0.56) | IDO1CYP2C9CYP2C8TDO2CYP3A4 | |
| SCHEMBL23707529 | 0.74 | CCNT1 (0.45) | IDO1CYP2C9CYP2C8TDO2CYP3A4 | |
| Hydrochloric Acid SCHEMBL23699162 | 0.73 | CCNT1 (0.39) | IDO1KCNH2 | |
| SCHEMBL22813012 | 0.72 | IDO1 (0.66) | IDO1CYP2C9CYP2C8TDO2CYP3A4 | |
| SCHEMBL23699141 | 0.71 | IDO1 (0.44) | IDO1 | |
| SCHEMBL23707415 | 0.71 | MAPT (0.39) | IDO1CYP2C9CYP2C8TDO2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379052-A1 | QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2021-12-09 | — | — | US | disclosed |
| EP-3858813-A1 | QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379052-A1 | QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY | IDO1, IDO2, INMT | IDO1 1/4885CYP2C9 1821/4885CYP2C8 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.