Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.61 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.61 |
| ▸ | SHBG | P04278 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711106 | 1.00 | CYP19A1 (0.61) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL23723902 | 1.00 | CYP19A1 (0.61) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL25247943 | 1.00 | CYP19A1 (0.61) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL4104457 | 0.86 | SHBG (0.71) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL1899132 | 0.86 | SHBG (0.71) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL1901199 | 0.86 | SHBG (0.71) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL23711138 | 0.86 | SHBG (0.71) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL1899136 | 0.86 | SHBG (0.71) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL13752813 | 0.86 | SHBG (0.71) | CYP19A1OR51E2SHBGHSD17B10LMNA | |
| SCHEMBL1331839 | 0.83 | CYP19A1 (0.74) | CYP19A1OR51E2SHBGHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212532-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-06 | — | — | US | disclosed |
| US-20230212532-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-06 | — | — | US | disclosed |
| EP-4100515-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | Bayer Aktiengesellschaft (DE) | 2022-12-14 | — | — | EP | disclosed |
| CN-115052975-A | P450 BM3 monooxygenase variants for C19-hydroxylation of steroids | 拜耳公司 | 2022-09-13 | — | — | CN | disclosed |
| WO-2021156200-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021156200-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-12 | — | — | WO | disclosed |
| EP-3858986-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | Bayer Aktiengesellschaft (DE) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858986-A1 | P450 BM3 MONOOXYGENASE VARIANTS FOR C19-HYDROXYLATION OF STEROIDS | Bayer Aktiengesellschaft (DE) | 2021-08-04 | — | — | EP | disclosed |