Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699257 | 1.00 | CCR1 (0.44) | CCR1SLC6A2SLC6A4OPRM1OPRL1 | |
| SCHEMBL23699228 | 0.93 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL23719123 | 0.93 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL23699229 | 0.93 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL23719110 | 0.93 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL23699319 | 0.93 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL23699243 | 0.93 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| Hydrochloric Acid SCHEMBL23699211 | 0.92 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| Hydrochloric Acid SCHEMBL23699209 | 0.92 | OPRM1 (0.44) | SLC6A2SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL23699395 | 0.89 | OPRM1 (0.44) | CCR1SLC6A2SLC6A4OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | claimed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |