Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699373 | 0.90 | SYK (0.54) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL3825012 | 0.86 | ATM (0.55) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL1186455 | 0.86 | ATM (0.55) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL825959 | 0.86 | ATM (0.55) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL8239858 | 0.85 | CTSK (0.56) | CTSKCTSSSYKATMSIGMAR1 | |
| SCHEMBL18085403 | 0.85 | CTSK (0.54) | CTSKCTSSSYKMEN1KMT2A | |
| SCHEMBL2548413 | 0.84 | CTSK (0.58) | CTSKCTSSSYKATMSIGMAR1 | |
| SCHEMBL2548417 | 0.84 | CTSK (0.58) | CTSKCTSSSYKATMSIGMAR1 | |
| SCHEMBL1627707 | 0.80 | SYK (0.67) | CTSKCTSSSYKMEN1KMT2A | |
| SCHEMBL31757814 | 0.79 | MEN1 (0.46) | CTSKCTSSSYKMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| CN-106029672-A | Serine/threonine kinase inhibitors | 基因泰克公司 | 2016-10-12 | — | — | CN | disclosed |