Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699315 | 1.00 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL23699391 | 1.00 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL9439279 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL7407045 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL7316279 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL7346811 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL744269 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL13208509 | 0.84 | ATM (0.59) | ATMACECTSSCTSKCTSL | |
| SCHEMBL851074 | 0.84 | ATM (0.59) | ATMACECTSSCTSKCTSL | |
| SCHEMBL2155967 | 0.84 | ATM (0.55) | ATMACECTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |