Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346811 | 1.00 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL7316279 | 1.00 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL9439279 | 1.00 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL7407045 | 1.00 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL7309827 | 0.91 | ATM (0.54) | ATMACECTSSCTSKCTSL | |
| SCHEMBL9737911 | 0.91 | ATM (0.54) | ATMACECTSSCTSKCTSL | |
| SCHEMBL1150914 | 0.91 | KLK5 (0.58) | ATMACECTSSCTSKCTSL | |
| SCHEMBL23699313 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL23699315 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL | |
| SCHEMBL23699391 | 0.86 | ATM (0.57) | ATMACECTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274423-A2 | Method for the production of crystalline amino-protected-beta-benzyl-L-aspartic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-07-13 | — | — | EP | claimed |
| US-4713480-A | Method for the production of crystalline amino-protected-beta-benzyl-L-aspartic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-12-15 | — | — | US | claimed |
| EP-2397488-B1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | FEDERAL STATE BUDGETARY INSTITUTION RES ZAKUSOV INSTITUTE OF PHARMACOLOGY (RU) | 2019-03-27 | — | — | EP | disclosed |
| US-9683014-B2 | Dipeptide mimetics of NGF and BDNF neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2017-06-20 | — | — | US | disclosed |
| EP-2431403-B1 | POLYMER CONJUGATE OF BIOACTIVE SUBSTANCE HAVING HYDROXY GROUP | NIPPON KAYAKU KK (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII (RU) | 2015-04-23 | — | — | US | disclosed |
| US-8808749-B2 | Polymer conjugate of bioactive substance having hydroxy group | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2014-08-19 | — | — | US | disclosed |
| CN-102421827-B | Polymer conjugate of bioactive substance having hydroxy group | NIPPON KAYAKU KK | 2014-07-30 | — | — | CN | disclosed |
| US-20120116051-A1 | Polymer Conjugate Of Bioactive Substance Having Hydroxy Group | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2012-05-10 | — | — | US | disclosed |
| CN-102421827-A | Polymer conjugate of bioactive substance having hydroxy group | NIPPON KAYAKU KK | 2012-04-18 | — | — | CN | disclosed |
| EP-2431403-A1 | POLYMER CONJUGATE OF BIOACTIVE SUBSTANCE HAVING HYDROXY GROUP | Nippon Kayaku Kabushiki Kaisha (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-0136879-A2 | Fatty acid derivatives and processes of producing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |
| US-4505853-A | GLANDULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |
| US-4369137-A | N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0042291-A2 | Methods and compositions for preparation of H-Arg-X-Z-Y-Tyr-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4301045-A | RESIN PEPTIDES | ARMOUR PHARMACEUTICAL COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4298523-A | OLIGOPEPTIDES OF ARGININE, LYSINE, VALINE, SARCOSINE, ASPARTIC OR GLUTAMIC ACID, AND TYROSINE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| US-4191808-A | DIPEPTIDE CONTAINING PROLINE AND A PHOTOMETRICALLY DETECTABLE NITROANILINE, PHENYLAZOANILINE OR PHENYLAZONAPHTHYLAMINE GROUP | AJINOMOTO CO., INC. (JP) | 1980-03-04 | — | — | US | disclosed |
| US-4161522-A | OLIGOPEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1979-07-17 | — | — | US | disclosed |
| US-4119620-A | Novel dipeptide derivatives, salts thereof, and method of measuring enzyme activity | AJINOMOTO CO., INC. (JP) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | ATM 3028/4885ACE 2496/4885CTSS 3014/4885 |
| US-20120116051-A1 | Polymer Conjugate Of Bioactive Substance Having Hydroxy Group | CTSL, CPA3, ADCY10 | ATM 3758/4885ACE 764/4885CTSS 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.