Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 16/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23719023 | 1.00 | OPRL1 (0.46) | OPRL1OPRM1OPRK1HRH3EPHX2 | |
| SCHEMBL23718991 | 1.00 | OPRL1 (0.46) | OPRL1OPRM1OPRK1HRH3EPHX2 | |
| SCHEMBL23719125 | 0.84 | OPRL1 (0.42) | OPRL1OPRM1OPRK1HRH3EPHX2 | |
| SCHEMBL23719074 | 0.76 | BACE1 (0.61) | OPRL1OPRM1OPRK1HRH3 | |
| SCHEMBL23719019 | 0.76 | BACE1 (0.61) | OPRL1OPRM1OPRK1HRH3 | |
| SCHEMBL23718993 | 0.75 | CCR5 (0.54) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL23699412 | 0.75 | BACE1 (0.60) | OPRL1OPRM1OPRK1HRH3 | |
| Hydrochloric Acid SCHEMBL23699247 | 0.75 | BACE1 (0.60) | OPRL1OPRM1OPRK1HRH3 | |
| Hydrochloric Acid SCHEMBL23699248 | 0.75 | BACE1 (0.60) | OPRL1OPRM1OPRK1HRH3 | |
| SCHEMBL27854074 | 0.73 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | claimed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |