Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699365 | 1.00 | OPRM1 (0.46) | OPRM1OPRL1HTTUSP2CYP3A4 | |
| SCHEMBL23699243 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL23699228 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL23719110 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL23719123 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL23699229 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL23699319 | 0.91 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| Hydrochloric Acid SCHEMBL23699211 | 0.90 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| Hydrochloric Acid SCHEMBL23699209 | 0.90 | OPRM1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRK1 | |
| SCHEMBL23699257 | 0.88 | CCR1 (0.44) | OPRM1OPRL1SLC6A2SLC6A4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | claimed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |