Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 13/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516007 | 0.86 | KIT (0.70) | KITPDGFRB | |
| SCHEMBL23699590 | 0.83 | KIT (0.52) | KITPDGFRB | |
| SCHEMBL15665162 | 0.82 | KIT (0.56) | KITPDGFRB | |
| SCHEMBL15665163 | 0.82 | KIT (0.72) | KIT | |
| SCHEMBL15664356 | 0.73 | KIT (0.80) | KITPDGFRB | |
| SCHEMBL15664562 | 0.71 | KIT (1.00) | KIT | |
| SCHEMBL5278122 | 0.71 | LMNA (0.67) | PDGFRB | |
| SCHEMBL15665145 | 0.69 | KIT (1.00) | KITPDGFRB | |
| SCHEMBL29230307 | 0.68 | KIT (0.65) | KITPDGFRB | |
| SCHEMBL15663586 | 0.68 | KIT (1.00) | KITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892534-B1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-08-04 | — | — | EP | claimed |