SCHEMBL23701231

SCHEMBL23701231

[SiH3]COC(Cl)C1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23092243 0.74 SHBG (0.41) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL23701174 0.74 EPHX1 (0.32) EPHX1SHBGTP53
SCHEMBL547689 0.72 EPHX1 (0.36) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL2000549 0.69 SHBG (0.39) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL20411178 0.67 SHBG (0.37) EPHX1SHBGTP53
SCHEMBL17966495 0.64
Cyclohexane SCHEMBL2027488 0.63 EPHX1 (0.41) EPHX1SHBGTP53KDM4EGMNN
SCHEMBL21279788 0.63 EPHX1 (0.41) EPHX1SHBGTP53KDM4EGMNN
Cyclohexane SCHEMBL6482192 0.63 EPHX1 (0.41) EPHX1SHBGTP53KDM4EGMNN
Cyclohexane SCHEMBL3485509 0.63 EPHX1 (0.41) EPHX1SHBGTP53KDM4EGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed