Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.74 |
| ▸ | MMP9 | P14780 | 19/20 | 0.74 |
| ▸ | MMP14 | P50281 | 15/20 | 0.74 |
| ▸ | MMP8 | P22894 | 9/20 | 0.71 |
| ▸ | MMP3 | P08254 | 4/20 | 0.71 |
| ▸ | MMP7 | P09237 | 3/20 | 0.71 |
| ▸ | MMP1 | P03956 | 1/20 | 0.68 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404560 | 0.87 | MMP2 (0.71) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL10238460 | 0.86 | MMP2 (0.79) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL16404575 | 0.85 | MMP2 (0.68) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL19771705 | 0.84 | MMP2 (0.74) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL10238443 | 0.83 | MMP2 (0.73) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL17623850 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL12290723 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL10238452 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL12747549 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP8MMP3 | |
| SCHEMBL17039264 | 0.82 | MMP2 (0.74) | MMP2MMP9MMP14MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109767-A2 | GELATINASE INHIBITORS AND PRODRUGS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-09-09 | — | — | WO | disclosed |