⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21678081 | 1.00 | — | — | |
| SCHEMBL3676503 | 0.89 | NPC1 (0.32) | — | |
| SCHEMBL13428276 | 0.89 | NPC1 (0.32) | — | |
| SCHEMBL14607913 | 0.89 | NPC1 (0.32) | — | |
| SCHEMBL21678184 | 0.87 | LATS1 (0.31) | — | |
| SCHEMBL23701691 | 0.87 | LATS1 (0.31) | — | |
| SCHEMBL21678070 | 0.86 | APP (0.31) | — | |
| SCHEMBL23701714 | 0.86 | APP (0.31) | — | |
| SCHEMBL23701688 | 0.82 | SNCA (0.36) | — | |
| SCHEMBL21678123 | 0.82 | SNCA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |