Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19743757 | 0.84 | LPL (0.39) | LPLLIPGP2RX7EGFR | |
| SCHEMBL12327389 | 0.84 | LPL (0.39) | LPLLIPGP2RX7EGFR | |
| SCHEMBL16534627 | 0.83 | LPL (0.38) | LPLLIPGP2RX7EGFR | |
| SCHEMBL22616641 | 0.83 | LPL (0.38) | LPLLIPGP2RX7EGFR | |
| SCHEMBL30959652 | 0.83 | LPL (0.38) | LPLLIPGP2RX7EGFR | |
| SCHEMBL8222881 | 0.83 | LPL (0.38) | LPLLIPGP2RX7EGFR | |
| SCHEMBL31651722 | 0.80 | LPL (0.36) | LPLLIPGP2RX7EGFR | |
| SCHEMBL28985657 | 0.79 | LPL (0.35) | LPLLIPGEGFR | |
| SCHEMBL31046590 | 0.79 | LPL (0.40) | LPLLIPGEGFR | |
| SCHEMBL2813914 | 0.79 | LPL (0.40) | LPLLIPGEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |