Styrene

Styrene

SCHEMBL2370337

C=CC(=O)OCCCC.C=Cc1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.54
HPGD P15428 1/20 0.54
THRB P10828 3/20 0.44
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 3/20 0.40
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
THRA P10827 1/20 0.38
APP P05067 1/20 0.38
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 1/20 0.37
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27994795 0.95 TSHR (0.48) TSHRHPGDTHRBALDH1A1CYP3A4
Styrene SCHEMBL3196230 0.90 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL67823 0.90 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL28887747 0.90 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3696057 0.90 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Maleic Anhydride SCHEMBL2371034 0.88 TSHR (0.69) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL11316570 0.87 MEN1 (0.43) TSHRHPGDTHRBL3MBTL1ALDH1A1
Styrene SCHEMBL3111143 0.87 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL4798421 0.87 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1
Maleic Anhydride SCHEMBL28490508 0.87 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020242132-A1 ENTERIC TABLET CONTAINING DIMETHYL FUMARATE 주식회사 큐라클 2020-12-03 WO claimed
CN-111683684-B Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-07-02 CN disclosed
CN-117599029-A Compositions for controlled release of cysteamine and systematic treatment of cysteamine-sensitive disorders 硫创治疗公司 2024-02-27 CN disclosed
CN-116854864-A Solvent-free water-based multifunctional amphoteric polymer, and preparation method and application thereof 严森开 2023-10-10 CN disclosed
CN-116348094-A Novel gastroretentive extended release dosage forms 诺施达制药股份有限公司 2023-06-27 CN disclosed
CN-115884764-A Cysteamine precursor compounds for treating coronavirus b infection 硫创治疗公司 2023-03-31 CN disclosed
WO-2020242132-A1 ENTERIC TABLET CONTAINING DIMETHYL FUMARATE 주식회사 큐라클 2020-12-03 WO disclosed
CN-111683684-A Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2020-09-18 CN disclosed
WO-2011112111-A1 PROCESS FOR OBTAINING A BINDER FOR FIBERS AND CURABLE BINDER FOR FIBERS MUNTEANU, REMUS (RO) 2011-09-15 WO disclosed
EP-1514547-A1 CONTROLLED-RELEASE DRUG COMPOSITION Kowa Co., Ltd. (JP) 2005-03-16 EP disclosed
CN-1151409-C Toner for developing electrostatic image, apparatus unit and image forming method 佳能株式会社 2004-05-26 CN disclosed
US-20040018235-A1 Controlled release pharmaceutical composition KOWA CO., LTD (JP) 2004-01-29 US disclosed
CN-1164050-A Toner for developing electrostatic image, apparatus unit and image forming method CANON KK (JP) 1997-11-05 CN disclosed