Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608851 | 0.90 | TDP1 (0.54) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL30648614 | 0.90 | METAP1 (0.50) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL29120739 | 0.90 | METAP1 (0.50) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL8206319 | 0.87 | TDP1 (0.55) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL14488028 | 0.86 | METAP1 (0.60) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL30960433 | 0.86 | TDP1 (0.54) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL29120741 | 0.85 | METAP1 (0.55) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL10057541 | 0.82 | TDP1 (0.63) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL18457178 | 0.80 | TDP1 (0.49) | METAP1TDP2PARP10TDP1L3MBTL1 | |
| SCHEMBL11176836 | 0.80 | TDP1 (0.49) | METAP1TDP2PARP10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| WO-2011107494-A1 | NOVEL AROMATIC GLYCOSIDE DERIVATIVES, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND THE USE THEREOF | SANOFI (FR) | 2011-09-09 | — | — | WO | disclosed |