Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | S100A4 | P26447 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | ROS1 | P08922 | 1/20 | 0.50 |
| ▸ | MARK3 | P27448 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.50 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761880 | 0.94 | METAP1 (0.65) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL394145 | 0.90 | TDP1 (0.80) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL8206319 | 0.87 | TDP1 (0.55) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL4254618 | 0.86 | METAP1 (0.71) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL358939 | 0.86 | TDP1 (0.81) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL29812691 | 0.85 | CHEK2 (0.57) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL3165396 | 0.85 | CHEK2 (0.57) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL31073 | 0.84 | METAP1 (0.79) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL25920001 | 0.84 | TDP1 (0.51) | TDP1L3MBTL1METAP1S100A4BCL2 | |
| SCHEMBL12117371 | 0.83 | CHEK2 (0.55) | TDP1L3MBTL1METAP1S100A4BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| WO-2012008557-A1 | NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | WO | disclosed |