Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS1 | P09382 | 2/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | PYGB | P11216 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 8/20 | 0.35 |
| ▸ | HEXB | P07686 | 2/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26893427 | 1.00 | LGALS1 (0.41) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL26698792 | 1.00 | LGALS1 (0.41) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL25867409 | 0.80 | LGALS1 (0.38) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL5444302 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL5444372 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL5446587 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL15370355 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL24115372 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL18383814 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB | |
| SCHEMBL24243426 | 0.71 | LGALS1 (0.59) | LGALS1LGALS3LGALS9LGALS8PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021155317-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2021-08-05 | — | — | WO | disclosed |