SCHEMBL23707278

SCHEMBL23707278

Cc1c(-c2ccccc2F)[nH]c2ccc(CN)cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
TUBB4A P04350 2/20 0.39
TUBB P07437 2/20 0.39
TUBA3C P0DPH7 2/20 0.39
TUBA1B P68363 2/20 0.39
TUBA4A P68366 2/20 0.39
TUBB4B P68371 2/20 0.39
TUBB3 Q13509 2/20 0.39
TUBB2A Q13885 2/20 0.39
TUBB8 Q3ZCM7 2/20 0.39
TUBA3E Q6PEY2 2/20 0.39
TUBA1A Q71U36 2/20 0.39
TUBA1C Q9BQE3 2/20 0.39
TUBB6 Q9BUF5 2/20 0.39
TUBB2B Q9BVA1 2/20 0.39
TUBB1 Q9H4B7 2/20 0.39
ALOX5 P09917 1/20 0.39
F2 P00734 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23704106 0.99 DRD2 (0.41) DRD2HTR2AHTR2CTUBB4ATUBB
Hydrochloric Acid SCHEMBL29994047 0.99 DRD2 (0.41) DRD2HTR2AHTR2CTUBB4ATUBB
SCHEMBL23707292 0.86 TLR9 (0.47) ALOX5F2KIF11MAPTTLR9
Hydrochloric Acid SCHEMBL23704276 0.85 TLR9 (0.47) ALOX5F2KIF11MAPTTLR9
Hydrochloric Acid SCHEMBL29994160 0.85 TLR9 (0.47) ALOX5F2KIF11MAPTTLR9
SCHEMBL28864939 0.84 F2 (0.39) F2KIF11MAPTL3MBTL1TLR9
SCHEMBL30078539 0.83 FFAR1 (0.38) F2KIF11CNR1TLR9PRKCB
SCHEMBL23704301 0.83 FFAR1 (0.38) F2KIF11CNR1TLR9PRKCB
SCHEMBL23707344 0.83 F2 (0.40) F2KIF11MAPTTLR9PRKCB
SCHEMBL30078441 0.83 F2 (0.40) F2KIF11MAPTTLR9PRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 WO disclosed