Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063557 | 0.81 | L3MBTL1 (0.51) | L3MBTL1ASIC3HRH3HRH1HRH4 | |
| SCHEMBL3233668 | 0.77 | L3MBTL1 (0.65) | L3MBTL1HRH3HRH1HRH4KDM4E | |
| SCHEMBL4212164 | 0.76 | KDM4E (0.61) | L3MBTL1KDM4ETAAR1ALDH1A1MAPT | |
| SCHEMBL15081590 | 0.76 | L3MBTL1 (0.58) | L3MBTL1ASIC3HRH3HRH1HRH4 | |
| SCHEMBL64435 | 0.76 | L3MBTL1 (0.68) | L3MBTL1HRH3HRH1HRH4LMNA | |
| SCHEMBL29373231 | 0.76 | L3MBTL1 (0.68) | L3MBTL1HRH3HRH1HRH4LMNA | |
| SCHEMBL7083429 | 0.76 | L3MBTL1 (0.53) | L3MBTL1ASIC3HRH3HRH1HRH4 | |
| SCHEMBL30064008 | 0.75 | L3MBTL1 (0.49) | L3MBTL1HRH3HRH1HRH4ALDH1A1 | |
| SCHEMBL41191 | 0.75 | L3MBTL1 (0.59) | L3MBTL1ASIC3HRH3HRH1HRH4 | |
| SCHEMBL29830938 | 0.75 | L3MBTL1 (0.59) | L3MBTL1ASIC3HRH3HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |