SCHEMBL23707453

SCHEMBL23707453

CC(C(O)Nc1ccc(Cl)cc1)N1CC2C(C1)C2Oc1ccnc2ccc(F)cc12

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.53
CYP3A4 P08684 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24089848 0.83 IDO1 (0.65) IDO1CYP3A4
SCHEMBL23707490 0.83 IDO1 (0.65) IDO1CYP3A4
SCHEMBL23699138 0.78 IDO1 (0.61) IDO1CYP3A4
SCHEMBL23707515 0.78 IDO1 (0.45) IDO1CYP3A4
SCHEMBL23707521 0.77 IDO1 (0.64) IDO1
SCHEMBL23707461 0.73 IDO1 (0.55) IDO1CYP3A4
SCHEMBL24018264 0.73 IDO1 (0.90) IDO1
SCHEMBL23699164 0.72 IDO1 (0.60) IDO1
SCHEMBL23707432 0.72 IDO1 (0.65) IDO1CYP3A4
SCHEMBL17729160 0.71 IDO1 (0.66) IDO1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858813-A1 QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2021-08-04 EP disclosed