Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24089848 | 1.00 | IDO1 (0.65) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23707432 | 0.88 | IDO1 (0.65) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23707491 | 0.88 | IDO1 (0.59) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL17729160 | 0.86 | IDO1 (0.66) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23699138 | 0.85 | IDO1 (0.61) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL30444768 | 0.84 | IDO1 (0.62) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23699118 | 0.84 | IDO1 (0.62) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23707447 | 0.83 | IDO1 (0.55) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23699124 | 0.83 | IDO1 (0.55) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL23707453 | 0.83 | IDO1 (0.53) | IDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379052-A1 | QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2021-12-09 | — | — | US | disclosed |
| EP-3858813-A1 | QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379052-A1 | QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY | IDO1, IDO2, INMT | IDO1 1/4885CYP2C9 1821/4885CYP3A4 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.