Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | GFER | P55789 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | YWHAG | P61981 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959047 | 0.87 | CDC7 (0.58) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL11167415 | 0.83 | ALDH1A1 (0.60) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL6104306 | 0.83 | TSHR (0.49) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL17774819 | 0.81 | KDM4E (1.00) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL17774829 | 0.80 | HTT (1.00) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL12505443 | 0.80 | KDM4E (0.69) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL28325509 | 0.80 | HTT (0.71) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL23708584 | 0.79 | GAA (0.48) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL16234290 | 0.79 | HTT (0.69) | KDM4EMEN1KMT2AHSD17B10GFER | |
| SCHEMBL12505489 | 0.79 | HTT (0.69) | KDM4EMEN1KMT2AHSD17B10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |