Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.80 |
| ▸ | CDK9 | P50750 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | YWHAG | P61981 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CHUK | O15111 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23707895 | 0.85 | KDM4E (0.63) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL23707919 | 0.84 | MKNK1 (0.58) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL23708616 | 0.82 | CDC7 (0.59) | CDC7CDK9KDM4EMAPTHTT | |
| SCHEMBL23707892 | 0.79 | KDM4E (0.55) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL27946076 | 0.78 | CHUK (0.59) | CDC7CDK9CHUKROCK2MAP4K4 | |
| SCHEMBL23708489 | 0.78 | KDM4E (0.53) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL883907 | 0.77 | CDC7 (0.58) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL3627591 | 0.76 | NPC1 (0.61) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL17774819 | 0.75 | KDM4E (1.00) | CDC7CDK9KDM4EMEN1MAPT | |
| SCHEMBL28281279 | 0.75 | CDC7 (0.63) | CDC7CDK9MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |