Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | YWHAG | P61981 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223329 | 0.89 | CDC7 (0.63) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL23707892 | 0.79 | KDM4E (0.55) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL23708152 | 0.78 | CDC7 (0.80) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL8782056 | 0.77 | CSNK1A1 (0.54) | KDM4EGFERKMT2ACSNK1A1TYRO3 | |
| SCHEMBL23707895 | 0.74 | KDM4E (0.63) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL23707919 | 0.73 | MKNK1 (0.58) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL7427024 | 0.72 | CSNK1A1 (0.48) | KDM4EMAPTCDC7CSNK1A1TYRO3 | |
| SCHEMBL5224122 | 0.72 | ALDH1A1 (0.53) | KDM4EMEN1MAPTKMT2AHTT | |
| SCHEMBL2351161 | 0.70 | NISCH (0.53) | KDM4EMEN1MAPTTHRBALOX15 | |
| SCHEMBL17774819 | 0.70 | KDM4E (1.00) | KDM4EMEN1MAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |