Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GFER | P55789 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | YWHAG | P61981 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087577 | 0.86 | HTT (0.66) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL17113198 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL3086566 | 0.79 | HTT (0.57) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL17774819 | 0.79 | KDM4E (1.00) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL3081902 | 0.78 | HTT (0.56) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL17774829 | 0.78 | HTT (1.00) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL12505443 | 0.78 | KDM4E (0.69) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL28325509 | 0.78 | HTT (0.71) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL23708151 | 0.78 | KDM4E (0.69) | KDM4EHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL3089872 | 0.77 | CSF1R (0.55) | KDM4EHSD17B10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |