Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 9/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838858 | 0.86 | EPHX2 (0.51) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL18855867 | 0.82 | LIPE (0.53) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL647981 | 0.81 | EPHX2 (0.51) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL30805661 | 0.81 | EPHX2 (0.51) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL23207707 | 0.81 | EPHX2 (0.51) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL649932 | 0.81 | EPHX2 (0.51) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL30755072 | 0.81 | LIPE (0.52) | EPHX2LIPELIPGHPGDHSD11B1 | |
| SCHEMBL16839482 | 0.81 | LIPE (0.52) | EPHX2LIPELIPGHPGDHSD11B1 | |
| Hydrochloric Acid SCHEMBL23167679 | 0.80 | EPHX2 (0.50) | EPHX2LIPELIPGHPGDHSD11B1 | |
| Hydrochloric Acid SCHEMBL23167614 | 0.80 | EPHX2 (0.50) | EPHX2LIPELIPGHPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |