Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731578 | 0.83 | DRD4 (0.31) | DRD4 | |
| SCHEMBL22732907 | 0.82 | CHEK1 (0.35) | — | |
| SCHEMBL3403132 | 0.82 | CHEK1 (0.35) | — | |
| SCHEMBL27731609 | 0.82 | EPHX1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL23698679 | 0.81 | CHEK1 (0.34) | — | |
| SCHEMBL27731538 | 0.81 | EPHX1 (0.33) | DRD4 | |
| SCHEMBL23710155 | 0.80 | HTR2A (0.32) | — | |
| SCHEMBL27731600 | 0.79 | DRD4 (0.33) | DRD4 | |
| SCHEMBL24171558 | 0.76 | — | — | |
| SCHEMBL24170772 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858832-A1 | TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |