Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710366 | 0.89 | FOLH1 (0.47) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL26427320 | 0.89 | FOLH1 (0.47) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23710384 | 0.89 | FOLH1 (0.47) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23710442 | 0.84 | FOLH1 (0.45) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23704703 | 0.83 | FOLH1 (0.57) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6381693 | 0.82 | FOLH1 (0.51) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL26424068 | 0.81 | FOLH1 (0.49) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL26424221 | 0.80 | FOLH1 (0.46) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL26424317 | 0.78 | CETP (0.45) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL23705074 | 0.77 | FOLH1 (0.52) | FOLH1TSHRALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155167-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-08-05 | — | — | WO | disclosed |