Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710366 | 0.87 | FOLH1 (0.47) | CETPFOLH1ALDH1A1TSHRMAPK1 | |
| SCHEMBL23710384 | 0.87 | FOLH1 (0.47) | CETPFOLH1ALDH1A1TSHRMAPK1 | |
| SCHEMBL26427320 | 0.87 | FOLH1 (0.47) | CETPFOLH1ALDH1A1TSHRMAPK1 | |
| SCHEMBL26424316 | 0.87 | P2RY10 (0.36) | ALDH1A1CYP3A4LPAR1LPAR3P2RY10 | |
| SCHEMBL26424122 | 0.87 | P2RY10 (0.36) | ALDH1A1CYP3A4LPAR1LPAR3P2RY10 | |
| SCHEMBL26424068 | 0.84 | FOLH1 (0.49) | CETPFOLH1ALDH1A1CYP3A4TSHR | |
| SCHEMBL23704703 | 0.84 | FOLH1 (0.57) | FOLH1ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL6381693 | 0.80 | FOLH1 (0.51) | CETPFOLH1ALDH1A1TSHRMAPK1 | |
| SCHEMBL20214855 | 0.78 | MEN1 (0.45) | CETPFOLH1ALDH1A1MEN1HPGD | |
| SCHEMBL23710362 | 0.78 | FOLH1 (0.44) | CETPFOLH1ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128984-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES, INCLUDING INFLAMMATORY BOWEL DISEASE (IBD) | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V.V.I. (CZ) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128984-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES, INCLUDING INFLAMMATORY BOWEL DISEASE (IBD) | SLC10A2, GPBAR1, NR1H4 | CETP 291/4885FOLH1 828/4885ALDH1A1 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.