Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710534 | 0.91 | FOLH1 (0.48) | FOLH1HSD17B10CETPLMNAALDH1A1 | |
| SCHEMBL23710442 | 0.90 | FOLH1 (0.45) | FOLH1POLBHSD17B10CETPLMNA | |
| SCHEMBL23705074 | 0.90 | FOLH1 (0.52) | FOLH1CETPALDH1A1MEN1HPGD | |
| SCHEMBL14102848 | 0.89 | FOLH1 (0.51) | FOLH1HSD17B10CETPLMNAALDH1A1 | |
| SCHEMBL23710509 | 0.89 | FOLH1 (0.44) | FOLH1POLBCETPALDH1A1L3MBTL1 | |
| SCHEMBL26424221 | 0.86 | FOLH1 (0.46) | FOLH1HSD17B10CETPLMNAALDH1A1 | |
| SCHEMBL7054189 | 0.84 | LMNA (0.46) | FOLH1HSD17B10CETPLMNAALDH1A1 | |
| SCHEMBL26424198 | 0.83 | FOLH1 (0.55) | FOLH1HSD17B10CETPALDH1A1TSHR | |
| SCHEMBL29520381 | 0.83 | FOLH1 (0.48) | FOLH1POLBHSD17B10CETPLMNA | |
| SCHEMBL4275480 | 0.83 | FOLH1 (0.67) | FOLH1HSD17B10CETPLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155167-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-08-05 | — | — | WO | disclosed |