Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509428 | 0.82 | ALDH1A1 (0.37) | ALDH1A1NPC1 | |
| SCHEMBL24850511 | 0.81 | ALDH1A1 (0.36) | EPHX2ALDH1A1EPHX1NPC1 | |
| SCHEMBL23842279 | 0.81 | EPHX2 (0.43) | EPHX2ALDH1A1EPHX1CHRNB2CHRNA3 | |
| SCHEMBL13045920 | 0.79 | EPHX2 (0.47) | EPHX2ALDH1A1EPHX1CHRNB2CHRNA3 | |
| SCHEMBL24935704 | 0.79 | EPHX2 (0.42) | EPHX2EPHX1 | |
| SCHEMBL27195367 | 0.79 | LPAR5 (0.32) | ALDH1A1NPC1 | |
| SCHEMBL17624387 | 0.74 | EPHX1 (0.40) | ALDH1A1EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL7487836 | 0.74 | EPHX2 (0.53) | EPHX2ALDH1A1EPHX1CHRNB2CHRNA3 | |
| SCHEMBL14996187 | 0.74 | EPHX2 (0.53) | EPHX2ALDH1A1EPHX1CHRNB2CHRNA3 | |
| SCHEMBL10282539 | 0.74 | ALDH1A1 (0.67) | EPHX2ALDH1A1EPHX1CHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155050-A1 | KINASE MODULATORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2021-08-05 | — | — | WO | disclosed |