Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24572096 | 0.86 | CRBN (0.56) | CRBNIKZF2IKZF1 | |
| SCHEMBL23710974 | 0.83 | IKZF2 (0.64) | CRBNIKZF2IKZF1 | |
| SCHEMBL20046855 | 0.82 | CRBN (0.57) | CRBNIKZF2IKZF1 | |
| SCHEMBL23710977 | 0.81 | IKZF2 (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL30579697 | 0.81 | CRBN (0.53) | CRBNIKZF2IKZF1 | |
| SCHEMBL25396789 | 0.81 | CRBN (0.53) | CRBNIKZF2IKZF1 | |
| SCHEMBL20046862 | 0.81 | CRBN (0.55) | CRBNIKZF2IKZF1 | |
| SCHEMBL23711044 | 0.81 | IKZF2 (0.61) | CRBNIKZF2IKZF1 | |
| SCHEMBL23710930 | 0.80 | IKZF2 (0.60) | CRBNIKZF2IKZF1 | |
| SCHEMBL30851290 | 0.79 | CRBN (0.56) | CRBNIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155050-A1 | KINASE MODULATORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2021-08-05 | — | — | WO | disclosed |