Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21702176 | 1.00 | CTSL (0.49) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL21702035 | 0.96 | CTSL (0.48) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL26494831 | 0.96 | CTSL (0.48) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL26494777 | 0.93 | CTSL (0.47) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL21702266 | 0.91 | CTSL (0.47) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL23506398 | 0.91 | CTSL (0.47) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL26494560 | 0.91 | CTSL (0.48) | CTSLCTSSCTSKRENF2RL1 | |
| SCHEMBL26494573 | 0.91 | CTSL (0.46) | CTSLCTSSCTSKRENF2RL1 | |
| SCHEMBL21702031 | 0.90 | CTSL (0.49) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL26494793 | 0.90 | CTSL (0.45) | CTSLCTSSCTSKCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151387-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | 中国科学院上海药物研究所 | 2021-08-05 | — | — | WO | disclosed |