Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 11/20 | 0.39 |
| ▸ | MAOA | P21397 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467584 | 1.00 | LMNA (0.39) | LMNAMAOBMAOAALDH1A1CACNA1F | |
| SCHEMBL10467518 | 0.79 | MAOB (0.44) | MAOBMAOAALDH1A1 | |
| SCHEMBL4524185 | 0.78 | LMNA (0.46) | LMNAMAOBMAOACACNA1FAR | |
| SCHEMBL10467519 | 0.77 | KDM1A (0.50) | KDM1A | |
| SCHEMBL6181548 | 0.75 | MAOB (0.36) | LMNAMAOBMAOAKDM1A | |
| SCHEMBL10467989 | 0.75 | LMNA (0.41) | LMNAMAOBALDH1A1THRBPKM | |
| SCHEMBL10467452 | 0.75 | LMNA (0.41) | LMNAMAOBALDH1A1THRBPKM | |
| SCHEMBL10467674 | 0.75 | LMNA (0.41) | LMNAMAOBALDH1A1THRBPKM | |
| SCHEMBL10467453 | 0.75 | LMNA (0.41) | LMNAMAOBALDH1A1THRBPKM | |
| SCHEMBL10467987 | 0.75 | LMNA (0.41) | LMNAMAOBALDH1A1THRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858816-A1 | NOVEL METHOD FOR PREPARING (-)-CIBENZOLINE SUCCINATE | Celltrion, Inc. (KR) | 2021-08-04 | — | — | EP | disclosed |