Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | RHEB | Q15382 | 4/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24996920 | 0.87 | GRIN1 (0.49) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL24996943 | 0.86 | GRIN1 (0.48) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL15506791 | 0.85 | GRIN1 (0.52) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL15520457 | 0.85 | GRIN1 (0.52) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL15506783 | 0.85 | GRIN1 (0.52) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL17206304 | 0.85 | GRIN1 (0.55) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL3605718 | 0.84 | GRIN1 (0.54) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL23111863 | 0.83 | GRIN1 (0.50) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL18520576 | 0.83 | GRIN1 (0.50) | GRIN1RHEBSMYD3NUDT1MLLT1 | |
| SCHEMBL15506666 | 0.83 | GRIN1 (0.50) | GRIN1RHEBSMYD3NUDT1MLLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718633-B2 | Indole compounds, process for the preparation and use thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-08-08 | — | — | US | disclosed |
| US-20230040909-A1 | INDOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20210238204-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718633-B2 | Indole compounds, process for the preparation and use thereof | IDO1, IDO2, INMT | GRIN1 4291/4885RHEB 1162/4885SMYD3 2030/4885 |
| US-20210238204-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | IDO1, IDO2, INMT | GRIN1 4291/4885RHEB 1162/4885SMYD3 2030/4885 |
| US-20230040909-A1 | INDOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | IDO1, IDO2, INMT | GRIN1 3574/4885RHEB 2161/4885SMYD3 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.