SCHEMBL2371278

SCHEMBL2371278

O=Cc1c(O)ccc(Br)c1Br

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 14/20 0.47
KDM4E B2RXH2 1/20 0.37
PTGS2 P35354 1/20 0.37
RAB9A P51151 1/20 0.37
ALOX15 P16050 2/20 0.35
ALOX12 P18054 1/20 0.35
PADI4 Q9UM07 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5311396 0.86 ERN1 (0.50) ERN1KDM4EPTGS2RAB9APADI4
SCHEMBL6900813 0.80 ERN1 (0.45) ERN1PADI4
SCHEMBL29743628 0.78 ERN1 (0.44) ERN1KDM4EPTGS2RAB9AALOX15
SCHEMBL29743687 0.78 ERN1 (0.46) ERN1KDM4EPTGS2RAB9A
SCHEMBL1390662 0.78 ERN1 (0.46) ERN1KDM4EPTGS2RAB9A
SCHEMBL276448 0.78 ERN1 (0.44) ERN1KDM4EPTGS2RAB9AALOX15
SCHEMBL21884804 0.78 ERN1 (0.44) ERN1KDM4EPTGS2RAB9A
SCHEMBL20607903 0.78 ERN1 (0.45) ERN1KDM4EPTGS2RAB9A
SCHEMBL12865750 0.78 ERN1 (0.44) ERN1KDM4EPTGS2RAB9APADI4
SCHEMBL17841523 0.78 ERN1 (0.44) ERN1KDM4EPTGS2RAB9APADI4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015189092-A1 (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS AGFA GRAPHICS NV (BE) 2015-12-17 WO disclosed
WO-2015173231-A1 (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS AGFA GRAPHICS NV (BE) 2015-11-19 WO disclosed
EP-2941349-A1 (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS AGFA Graphics NV (BE) 2015-11-11 EP disclosed
WO-2014106554-A1 (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS AGFA GRAPHICS NV (BE) 2014-07-10 WO disclosed
WO-2011113693-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-09-22 WO disclosed