SCHEMBL6900813

SCHEMBL6900813

O=Cc1c(Br)ccc(Br)c1Br

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.45
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PRKDC P78527 1/20 0.32
CYP2A6 P11509 1/20 0.31
PADI4 Q9UM07 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30600412 0.85 ERN1 (0.50) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL30826192 0.80 ERN1 (0.36) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL2371278 0.80 ERN1 (0.47) ERN1PADI4
SCHEMBL23647903 0.80 ALDH1A1 (0.44) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL12760904 0.75 ERN1 (0.49) ERN1ALDH1A1
SCHEMBL25286856 0.75 ERN1 (0.68) ERN1ALDH1A1PRKDC
SCHEMBL8401425 0.75 KIF11 (0.36) ERN1MEN1KMT2A
SCHEMBL30826221 0.75 ERN1 (0.62) ERN1ALDH1A1PRKDC
SCHEMBL610877 0.74 ALDH1A1 (0.48) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL1418396 0.74 ERN1 (0.42) ERN1ALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP disclosed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO disclosed