Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837826 | 0.84 | PEPD (0.61) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL5062623 | 0.83 | PEPD (0.80) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL8867308 | 0.83 | PEPD (0.55) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL8530522 | 0.83 | PEPD (0.59) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL18843562 | 0.82 | HDAC1 (0.57) | NPC1MAPTMEN1KMT2AHDAC1 | |
| SCHEMBL1953686 | 0.81 | ALDH1A1 (0.59) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL14051538 | 0.81 | ALDH1A1 (0.61) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL25230264 | 0.81 | NPC1 (0.61) | PEPDALDH1A1NPC1GAAMAPT | |
| SCHEMBL29990643 | 0.80 | PRSS1 (0.47) | PEPDALDH1A1NPC1GAAMEN1 | |
| SCHEMBL1276799 | 0.80 | MEN1 (0.47) | NPC1GAAMEN1KMT2APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025763-B | Adenosine compound, pharmaceutically acceptable salt or stereoisomer thereof and application | 中国人民解放军军事科学院军事医学研究院 | 2023-09-12 | — | — | CN | disclosed |
| WO-2021154948-A1 | PRODRUGS USEFUL IN ADOPTIVE CELL THERAPY | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-08-05 | — | — | WO | disclosed |