Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713998 | 0.86 | HIF1A (0.41) | HIF1AFDPSHDAC1HDAC6 | |
| SCHEMBL23701909 | 0.80 | HIF1A (0.39) | HIF1AFDPS | |
| SCHEMBL23701903 | 0.80 | HIF1A (0.47) | HIF1AFDPSTDP1HDAC1HDAC6 | |
| SCHEMBL23713996 | 0.80 | HIF1A (0.47) | HIF1AFDPSTDP1HDAC1HDAC6 | |
| SCHEMBL23701943 | 0.73 | HIF1A (0.47) | HIF1AFDPSTDP1HDAC1HDAC6 | |
| SCHEMBL23701945 | 0.71 | HIF1A (0.46) | HIF1AFDPSTDP1HDAC1HDAC6 | |
| SCHEMBL23713995 | 0.65 | HIF1A (0.58) | HIF1ATDP1HDAC1HDAC6 | |
| SCHEMBL1651954 | 0.64 | FDPS (0.45) | HIF1AFDPSTDP1HDAC1HDAC6 | |
| SCHEMBL6003408 | 0.61 | TSHR (0.38) | — | |
| SCHEMBL19214793 | 0.59 | MAPK1 (0.42) | HIF1AFDPSTDP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238187-A1 | AZIRIDINE CONTAINING EPOTHILONE ANALOGS, METHODS OF SYNTHESIS, METHODS OF TREATMENT, AND DRUG CONJUGATES | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238187-A1 | AZIRIDINE CONTAINING EPOTHILONE ANALOGS, METHODS OF SYNTHESIS, METHODS OF TREATMENT, AND DRUG CONJUGATES | EPOR, EZR, CD47 | HIF1A 2854/4885FDPS 1142/4885TDP1 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.