Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 11/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | XIAP | P98170 | 8/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101583 | 1.00 | BIRC2 (0.46) | BIRC2PIK3CDXIAPCHRM1HRH3 | |
| SCHEMBL27320502 | 0.84 | BIRC2 (0.47) | BIRC2XIAPMLNRCYP3A4 | |
| SCHEMBL8733534 | 0.84 | BIRC2 (0.44) | BIRC2XIAPCHRM1 | |
| SCHEMBL3109196 | 0.82 | BIRC2 (0.42) | BIRC2XIAPCHRM1MLNR | |
| SCHEMBL17906594 | 0.82 | BIRC2 (0.49) | BIRC2XIAPCHRM1MLNRCYP3A4 | |
| SCHEMBL27341041 | 0.82 | BIRC2 (0.49) | BIRC2XIAPCHRM1MLNRCYP3A4 | |
| SCHEMBL13766678 | 0.82 | BIRC2 (0.45) | BIRC2XIAPCHRM1 | |
| SCHEMBL10730345 | 0.82 | BIRC2 (0.45) | BIRC2XIAPCHRM1 | |
| SCHEMBL3098422 | 0.81 | BIRC2 (0.41) | BIRC2XIAP | |
| Hydrochloric Acid SCHEMBL27151220 | 0.80 | BIRC2 (0.47) | BIRC2XIAPCHRM1MLNRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |
| WO-2021154668-A1 | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-08-05 | — | — | WO | disclosed |