Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591708 | 0.86 | OPRK1 (0.37) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL30041415 | 0.86 | OPRK1 (0.37) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL23705904 | 0.81 | PIK3CA (0.35) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL23705905 | 0.79 | PIK3CA (0.34) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL16926840 | 0.75 | PIK3C3 (0.46) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL473906 | 0.73 | KDM4E (0.46) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL18068209 | 0.73 | SMN1; SMN2 (0.52) | OPRK1ALDH1A1 | |
| SCHEMBL30963156 | 0.73 | KDM4E (0.46) | MEN1KMT2APIK3C3OPRK1ALDH1A1 | |
| SCHEMBL17001153 | 0.72 | PIK3C3 (0.34) | PIK3C3OPRK1ALDH1A1 | |
| SCHEMBL18634029 | 0.72 | PIK3C3 (0.33) | PIK3C3OPRK1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |