Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926946 | 0.89 | NOTUM (0.35) | PARP1NOTUM | |
| SCHEMBL8011587 | 0.79 | PARP1 (0.37) | PARP1NR3C1PGRNR3C2CYP2A6 | |
| SCHEMBL12078457 | 0.79 | PARP1 (0.58) | PARP1NR3C1PGRNR3C2CYP2A6 | |
| SCHEMBL3643840 | 0.76 | PARP1 (0.46) | PARP1 | |
| SCHEMBL30748780 | 0.76 | PARP1 (0.42) | PARP1NR3C1PGRNR3C2 | |
| SCHEMBL30467095 | 0.76 | PARP1 (0.39) | PARP1NR3C1PGRNR3C2CYP2A6 | |
| SCHEMBL12330400 | 0.76 | NOTUM (0.36) | PARP1NOTUMNR3C1PGRNR3C2 | |
| SCHEMBL18509016 | 0.76 | SELL (0.39) | PARP1NR3C1PGRNR3C2CYP2A6 | |
| SCHEMBL2464027 | 0.76 | PARP1 (0.39) | PARP1NR3C1PGRNR3C2CYP2A6 | |
| SCHEMBL24200079 | 0.76 | PARP1 (0.35) | PARP1NR3C1PGRNR3C2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |