Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854489 | 0.88 | CYP19A1 (0.36) | MEN1GAAKMT2A | |
| SCHEMBL24950149 | 0.88 | HDAC3 (0.37) | GAA | |
| SCHEMBL9943141 | 0.81 | ALDH1A1 (0.34) | — | |
| SCHEMBL26242999 | 0.80 | ALDH1A1 (0.34) | — | |
| SCHEMBL25918038 | 0.80 | PAOX (0.38) | MEN1GAAKMT2APTGER4PTGER3 | |
| SCHEMBL18287469 | 0.79 | PTGER4 (0.47) | MEN1KMT2APTGER4PTGER3PTGER2 | |
| SCHEMBL19773605 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL19287544 | 0.79 | BRD4 (0.37) | — | |
| SCHEMBL19522946 | 0.79 | CYP19A1 (0.37) | MEN1GAAKMT2APTGER4PTGER3 | |
| SCHEMBL20684234 | 0.79 | FOLH1 (0.43) | PTGS1PTGS2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858387-A1 | MONOMETHYLVALINE COMPOUNDS CAPABLE OF CONJUGATION TO LIGANDS | Seagen Inc. (US) | 2021-08-04 | — | — | EP | disclosed |