⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21141913 | 0.86 | ESR1 (0.32) | — | |
| SCHEMBL23714760 | 0.86 | ERN1 (0.41) | — | |
| SCHEMBL24327210 | 0.86 | ERN1 (0.37) | — | |
| SCHEMBL27897162 | 0.77 | ERN1 (0.39) | — | |
| SCHEMBL23603879 | 0.77 | NMT1 (0.32) | — | |
| SCHEMBL31117200 | 0.77 | ESR1 (0.34) | — | |
| SCHEMBL24094408 | 0.72 | MAPT (0.30) | — | |
| SCHEMBL1051454 | 0.71 | DGAT1 (0.39) | — | |
| SCHEMBL31548069 | 0.71 | DGAT1 (0.39) | — | |
| SCHEMBL2286127 | 0.71 | ERN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155320-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |