Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704928 | 0.86 | ALDH1A1 (0.33) | — | |
| SCHEMBL23705674 | 0.86 | CYP1A2 (0.37) | HPGDMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL23704812 | 0.77 | SLC6A4 (0.36) | HTTMEN1CYP2C19KMT2AMAOA | |
| SCHEMBL21505399 | 0.75 | METAP1 (0.39) | HPGDHTTMEN1CYP2C19KMT2A | |
| SCHEMBL31064458 | 0.70 | ALDH1A1 (0.30) | MAPT | |
| SCHEMBL31554124 | 0.68 | KMT2A (0.40) | KMT2AMAPT | |
| SCHEMBL23714874 | 0.67 | PBRM1 (0.35) | MAOAMAPT | |
| SCHEMBL19586504 | 0.66 | KMT2A (0.38) | HPGDHTTMEN1KMT2AMAOA | |
| SCHEMBL10048460 | 0.64 | ELANE (0.39) | MEN1KMT2AMAPT | |
| SCHEMBL31554234 | 0.63 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |