Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976812 | 0.95 | MME (0.44) | MMECACNA1HCNR2P2RX7DPP4 | |
| SCHEMBL13941597 | 0.91 | — | — | |
| SCHEMBL15502281 | 0.82 | ALDH1A1 (0.35) | MMEP2RX7ALDH1A1HTT | |
| SCHEMBL15461395 | 0.81 | DPP4 (0.40) | MMEDPP4ALDH1A1 | |
| SCHEMBL7400386 | 0.79 | CYP1A2 (0.34) | MME | |
| SCHEMBL18131263 | 0.79 | MME (0.41) | MMECACNA1HCNR2CNR1DPP4 | |
| SCHEMBL30325251 | 0.78 | MME (0.42) | MMECACNA1HCNR2CNR1DPP4 | |
| SCHEMBL23367152 | 0.78 | MME (0.33) | MMEP2RX7ALDH1A1HTT | |
| SCHEMBL20462577 | 0.77 | MME (0.38) | MMECACNA1HCNR2CNR1DPP4 | |
| SCHEMBL7724887 | 0.77 | CYP4F2 (0.36) | MMEP2RX7ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348447-A | Inhibitors of APOL1 and methods of using the same | 弗特克斯药品有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021154997-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-08-05 | — | — | WO | disclosed |