Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664346 | 0.74 | S1PR3 (0.49) | GAATHRB | |
| SCHEMBL20157091 | 0.73 | KMT2A (0.47) | GAATHRBHPGDHSD17B10KDR | |
| SCHEMBL4312347 | 0.68 | MAPKAPK2 (0.56) | GAATHRBHPGDHSD17B10ALDH1A1 | |
| SCHEMBL2054165 | 0.68 | MAPKAPK2 (0.56) | GAATHRBHPGDHSD17B10ALDH1A1 | |
| SCHEMBL17664408 | 0.66 | DPP4 (0.45) | ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL10435470 | 0.65 | CFTR (0.50) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15570094 | 0.65 | GAA (0.51) | GAATHRBHPGDHSD17B10PSMB5 | |
| SCHEMBL23780410 | 0.65 | HDAC3 (0.41) | HPGDHSD17B10ALDH1A1KMT2AMAPKAPK2 | |
| SCHEMBL23291971 | 0.65 | HDAC3 (0.41) | HPGDHSD17B10ALDH1A1KMT2AMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL9596127 | 0.64 | CFTR (0.49) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |