Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458580 | 0.88 | KMT2A (0.49) | KMT2AGCKKDM4EHSD17B10TSHR | |
| SCHEMBL10788485 | 0.80 | CYP1A2 (0.61) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL45148 | 0.79 | KMT2A (0.73) | KMT2AMEN1ALDH1A1KDM4ESIRT2 | |
| SCHEMBL29238994 | 0.78 | KMT2A (0.71) | KMT2AMEN1ALDH1A1KDM4ESIRT2 | |
| SCHEMBL30533391 | 0.78 | KMT2A (0.71) | KMT2AMEN1ALDH1A1KDM4ESIRT2 | |
| SCHEMBL14809359 | 0.77 | TSHR (0.54) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL11033096 | 0.74 | RAB9A (0.70) | KMT2AMEN1KDM4ESIRT2HSD17B10 | |
| SCHEMBL20141389 | 0.74 | KDM4E (0.42) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL5783437 | 0.74 | NAMPT (0.65) | KMT2AALDH1A1GAAKDM4ERAB9A | |
| SCHEMBL23715855 | 0.73 | GAA (0.40) | KMT2AMEN1ALDH1A1HPGDGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |